Peak 15 Bio

Learn

The science behind Peak 15 Bio, explained

Short, referenced explainers for clinicians, investors and partners on the cells, the disease and the technology.

ScienceWhat are endothelial colony-forming cells (ECFCs)?Endothelial colony-forming cells (ECFCs) are the body's blood-vessel builders. What they are, why they matter for brain injury, and why they have been hard to manufacture — until now.Read → DiseaseNeonatal HIE: a leading cause of lifelong disability with no approved medicineHypoxic-ischaemic encephalopathy (HIE) affects over a million newborns a year. Therapeutic hypothermia is the only treatment. The burden, the limits of cooling and the cell therapies now in development.Read → DeliveryIntranasal delivery: a non-invasive route to the injured brainHow intranasal delivery carries therapeutic cells past the blood–brain barrier via olfactory and trigeminal pathways — no surgery, no catheter — and why it suits fragile newborns and repeat dosing.Read → ManufacturingFrom one donor to a thousand doses: manufacturing ECFC therapy at scaleAllogeneic cell therapies have been held back by cost, consistency and supply. Our source tissue — abundant, ethically sourced and rich in high-proliferative-potential ECFCs — lets Can-Vas turn a single donation into 1,000+ off-the-shelf doses.Read →

Partner with us

We work with investors, clinicians, industry and patient communities who share our conviction that the earliest injuries deserve the most ambitious medicine.

General & partnering: info@peak15bio.com
Follow Peak 15 Bio on LinkedIn